产品货号：
GS4431
中文名称：
重组人PTH1-34
英文名称：
Recombinant Human Parathyroid Hormone 1-34
产品规格：
20μg
发货周期：
1～3天
产品价格：
询价
General Description:
Parathyroid hormone (PTH) is a single polypeptide of 84 amino acids.It is a critical hormone in the regulation of Ca2+ homeostasis,secreted by the parathyroid glands,which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts,indirectly promote increased intestinal absorption of calcium,and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates.It is a major regulator of bone metabolism.Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low.The amino terminal (1-34) fragment of parathyroid hormone,called PTH (1-34) reproduces all the activity of the full length mature hormone and has been used therapeutically for treatment of osteoporosis.
Storage:
This lyophilized preparation is stable at 2～8℃,but should be kept at -20℃ for long term storage,preferably desiccated.
Upon reconstitution,the preparation is stable for up to one week at 2～8℃.For maximal stability,apportion the reconstituted preparation into working aliquots and store at -20℃ to -70℃.Avoid repeated freeze/thaw cycles.
Usage:
This material is offered by bjbalb Biotech for research,laboratory or further evaluation purposes.
NOT FOR HUMAN USE.
Molecular Weight:
Approximately 4.1kDa,a single non-glycosylated polypeptide chain containing 34 amino acids.
Purity:
> 97% by SDS-PAGE and HPLC analyses.
Source:
Escherichia coli.
Biological Activity:
Fully biologically active when compared to standard.The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50ng/mL,corresponding to a specific activity of> 2.0×104 IU/mg.
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:
Lyophilized from a 0.2μm filtered concentrated solution in PBS,pH7.0.
Endotoxin:
Less than 1EU/μg of rHuPTH1-34 as determined by LAL method.
Reconstitution:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1～1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.
Further dilutions should be made in appropriate buffered solutions.
AA Sequence:
SVSEIQLMHN LGKHLNSMER VEWLRKKLQD VHNF
相关搜索：重组人PTH1-34，rhuPTH1-34，rhPTH1-34，Recombinant Human Parathyroid Hormone 1-34
Parathyroid hormone (PTH) is a single polypeptide of 84 amino acids.It is a critical hormone in the regulation of Ca2+ homeostasis,secreted by the parathyroid glands,which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts,indirectly promote increased intestinal absorption of calcium,and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates.It is a major regulator of bone metabolism.Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low.The amino terminal (1-34) fragment of parathyroid hormone,called PTH (1-34) reproduces all the activity of the full length mature hormone and has been used therapeutically for treatment of osteoporosis.
Storage:
This lyophilized preparation is stable at 2～8℃,but should be kept at -20℃ for long term storage,preferably desiccated.
Upon reconstitution,the preparation is stable for up to one week at 2～8℃.For maximal stability,apportion the reconstituted preparation into working aliquots and store at -20℃ to -70℃.Avoid repeated freeze/thaw cycles.
Usage:
This material is offered by bjbalb Biotech for research,laboratory or further evaluation purposes.
NOT FOR HUMAN USE.
Molecular Weight:
Approximately 4.1kDa,a single non-glycosylated polypeptide chain containing 34 amino acids.
Purity:
> 97% by SDS-PAGE and HPLC analyses.
Source:
Escherichia coli.
Biological Activity:
Fully biologically active when compared to standard.The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50ng/mL,corresponding to a specific activity of> 2.0×104 IU/mg.
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:
Lyophilized from a 0.2μm filtered concentrated solution in PBS,pH7.0.
Endotoxin:
Less than 1EU/μg of rHuPTH1-34 as determined by LAL method.
Reconstitution:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1～1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.
Further dilutions should be made in appropriate buffered solutions.
AA Sequence:
SVSEIQLMHN LGKHLNSMER VEWLRKKLQD VHNF
相关搜索：重组人PTH1-34，rhuPTH1-34，rhPTH1-34，Recombinant Human Parathyroid Hormone 1-34